(heparan sulfate)-glucosamine 3-sulfotransferase 1
In enzymology, a -glucosamine 3-sulfotransferase 1 is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and heparan sulfate-glucosamine, whereas its two products are adenosine 3',5'-bisphosphate and heparan sulfate-glucosamine 3-sulfate.
This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:-glucosamine 3-sulfotransferase. Other names in common use include heparin-glucosamine 3-O-sulfotransferase, 3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase, glucosaminyl 3-O-sulfotransferase, heparan sulfate D-glucosaminyl 3-O-sulfotransferase, and isoform/isozyme 1 . This enzyme participates in heparan sulfate biosynthesis and glycan structures - biosynthesis 1.As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.
