1-alkyl-2-acetylglycerophosphocholine esterase
In enzymology, a 1-alkyl-2-acetylglycerophosphocholine esterase is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine and H2O, whereas its two products are 1-alkyl-sn-glycero-3-phosphocholine and acetate. The former is also known as platelet-activating factor. There are multiple enzymes with this function:
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase. Other names in common use include 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase, and alkylacetyl-GPC:acetylhydrolase. This enzyme participates in ether lipid metabolism.As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes,,,,,, and.
