On September 28, 1935, Minnesota opened its season with a 26–6 victory over North Dakota Agricultural before a crowd of more than 34,000 at Memorial Stadium in Minneapolis. Minnesota scored four touchdowns, two by African-American left end Dwight T. Reed and one each by George Roscoe and right end Ray King. Despite the victory, the Associated Press, in its account of the game, opined that the Golden Gophers "lacked the flaming spirit to win" that marked the undefeated 1934 Minnesota team.
at Nebraska
On October 12, 1935, Minnesota defeated Dana X. Bible's Nebraska Cornhuskers, 12 to 7, at Memorial Stadium in Lincoln, Nebraska. George Roscoe returned the opening kickoff 74 yards and then scored on a lateral from Glenn Seidel. Early in the second quarter, Nebraska took the lead on a long touchdown run by quarterback Jerry LaNoue and an extra point. Roscoe ran for the winning touchdown later in the second quarter. Neither team scored in the second half. On defense, the Gophers kept Nebraska's highly touted halfback Lloyd Cardwell in check.
On October 19, 1935, Minnesota defeated Tulane, 20–0, before a crowd of 38,000 at Memorial Stadium in Minneapolis. The Gophers scored two touchdowns in the first quarter and another early in the second quarter, then spent the remainder of the game "in the roles of guinea pigs as their football professors made observations for future scientific operation when the going is tougher." Tulane totaled only two net rushing yards for the game. Minnesota captain Glenn Seidel suffered a broken collarbone in the game. Minnesota's touchdowns were scored by Sheldon Beise, Bud Wilkinson, and Clarence Thompson.
On October 26, 1935, Minnesota defeated Northwestern, 21 to 13, before a crowd of 52,000, one of the largest in Minnesota football history. Northwestern took a 13-7 lead at halftime, but sophomore right halfback Clarence Thompson led Minnesota's comeback in the second half. He scored a touchdown in the third quarter and then ran 36 yards for the winning touchdown in the fourth quarter.
Purdue
On November 2, 1935, Minnesota defeated Purdue, 29–7, in Minneapolis. Right halfback George Roscoe scored Minnesota's first touchdown in the first quarter. Left halfback Clarence Thompson also scored for Minnesota.
at Iowa
On November 9, 1935, Minnesota defeated Iowa, 13-6, in Iowa City.
On November 16, 1935, Minnesota defeated Michigan, 40–0, at Michigan Stadium. It was Minnesota's 23rd consecutive game without a loss and the worst defeat in the history of the Michigan football program since 1892. Minnesota gained 432 rushing yards to 99 for Michigan and also held Michigan to 35 passing yards. Clarence Thompson returned a kickoff 85 yards for a touchdown. Andrew Uram scored two touchdowns on runs of 60 and 73 yards. Sheldon Beise also scored two touchdowns. Vernal LeVoir scored on a 30-yard touchdown reception and kicked four extra points.
Wisconsin
On November 23, 1935, Minnesota defeated Wisconsin, 33-7, before a crowd of 45,000 spectators in Minneapolis. The victory was the 17th in a row for Minnesota and the 24th consecutive game without a defeat. Minnesota out-gained Wisconsin, 209 yards to 13 yards.
Postseason
Total attendance for the season was 217,785, which averaged to 43,557. The season high for attendance was against Northwestern.
