2010 Regional League Division 2 Central & Eastern Region
2010 Regional League Division 2 Central & Eastern Region is the 2nd season of the League competition since its establishment in 2009. It is in the third tier of the Thai football league system.
The league has been expanded from 12 clubs in 2009 to 16 clubs this season. The league winners and runners up will qualify for the 2010 Regional League Division 2 championship stage.
Changes from Last Season
Team Changes
Relocated Clubs
- Thai Summit Samut Prakan and Rose Asia Pathum Thani re-located to the Regional League Bangkok Area Division 2010.
- Prachuap Khiri Khan re-located to the Regional League Southern Region 2010
Expansion Clubs
Stadium and locations
| Team | Location | Stadium | Capacity | |
| Ang Thong | Ang Thong | Ang Thong Province Stadium | 5,500 | |
| Ayutthaya | Ayutthaya | Ayutthaya Province Stadium | 6,000 | |
| Cha Choeng Sao | Chachoengsao | Subin Pimpayachan Stadium | ? | |
| Lopburi | Lopburi | Phra Ramesuan Stadium | ? | |
| Kabinburi | Prachinburi | Nom Klao Maharaj Stadium | 3,000 | |
| Muangkan | Kanchanaburi | Kanchanaburi Stadium | 13,000 | |
| Nakhon Nayok | Nakhon Nayok | Nakhon Nayok Province Stadium | 2,406 | |
| Phetchaburi | Phetchaburi | Donkhan Stadium | 3,500 | |
| Saraburi | Saraburi | Saraburi Stadium | 6,000 | |
| Prachinburi United | Prachinburi | Prachinburi Province Stadium | 3,000 | |
| Pathum Thani | Pathum Thani | Thammasat Stadium | 25,000 | |
| Ratchaburi | Ratchaburi | Ratchaburi Province Stadium | 10,373 | |
| Rayong | Rayong | Rayong Province Stadium | 7,000 | |
| Sa Kaeo United | Sa Kaeo | Aranyaprathet District Stadium | ? | |
| Samut Prakan | Samut Prakan | Customs Department Stadium Samut Prakarn SAT Stadium | 3,500 2,000 | |
| Samut Sakhon | Samut Sakhon | IPE Samut Sakhon Stadium | 3,000 |