2016 Western & Southern Open – Men's Singles
was the two-time defending champion, but withdrew because of a knee injury.
Twelfth-seeded Marin Čilić won his maiden Masters 1000 title by defeating Andy Murray in the final, 6–4, 7–5. This also ended a streak of 18 consecutive Masters events won by a member of the Big Four.Seeds
The top eight seeds receive a bye into the second round.Draw
Finals
Top half
Section 1
Section 2
Section 3
Section 4
Seeds
Qualifiers
Qualifying draw
First qualifier
Second qualifier
Third qualifier
Fifth qualifier
Sixth qualifier