2020–21 South of Scotland Football League
The 2020–21 South of Scotland Football League will be the 75th season of the South of Scotland Football League, and the 7th season as the sixth tier of the Scottish football pyramid system. Stranraer reserves continue as the reigning champions due to the previous season being declared null and void.
Teams
The following teams changed division after the 2019–20 season.From South of Scotland League
Transferred to West of Scotland League| Team | Location | Home ground | Capacity | Seats | Floodlit |
| Abbey Vale | New Abbey | Maryfield Park | 1,000 | 0 | No |
| Caledonian Braves reserves | Motherwell | Alliance Park | 500 | 100 | Yes |
| Creetown | Creetown | Castlecary Park | 1,000 | 0 | No |
| Heston Rovers | Dumfries | Palmerston Park | 8,690 | 3,377 | Yes |
| Lochar Thistle | Dumfries | North West Community Campus | 1,000 | 0 | Yes |
| Lochmaben | Lochmaben | Whitehills Park | 1,000 | 0 | No |
| Mid-Annandale | Lockerbie | New King Edward Park | 1,000 | 0 | Yes |
| Newton Stewart | Newton Stewart | Blairmount Park | 1,500 | 0 | Yes |
| Nithsdale Wanderers | Sanquhar | Lorimer Park | 1,000 | 0 | Yes |
| St Cuthbert Wanderers | Kirkcudbright | St Mary's Park | 2,000 | 0 | Yes |
| Stranraer reserves | Stranraer | Stair Park | 4,178 | 1,830 | Yes |
| Threave Rovers | Castle Douglas | Meadow Park | 1,500 | Yes | |
| Upper Annandale | Moffat | Moffat Academy | 1,000 | 0 | No |
| Wigtown & Bladnoch | Wigtown | Trammondford Park | 888 | 0 | No |
Club has an SFA Licence and are eligible to participate in the Lowland League promotion play-off should they win the league. Caledonian Braves reserves and Stranraer reserves are ineligible for promotion.