4,4'-Biphenol
4,4'-Biphenol is an organic compound which is a phenolic derivative of biphenyl. It is a colorless solid.
4,4'-Biphenol is prepared by dealkylation of the tetra t-butyl derivative, generated by the oxidative coupling of 2,6-di-tert-butylphenol. The oxidative coupling of phenol itself typically gives a mixture of isomers. For example, VCl4 reacts with phenols give 4,4'-, 2,4'-, and 2,2'-biphenols:
An earlier process using oxygen and copper salts to enable the oxidative coupling was reportedSafety
Vanadium chloride is estrogenic and cytotoxic.
