AP3B1


AP-3 complex subunit beta-1 is a protein that in humans is encoded by the AP3B1 gene.

Function

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky–Pudlak syndrome type 2.

Interactions

AP3B1 has been shown to interact with AP3S2.