AP4B1


AP-4 complex subunit beta-1 is a protein that in humans is encoded by the AP4B1 gene.

Function

The heterotetrameric adaptor protein complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 and epsilon-4, a medium chain, mu-4, and a small chain, sigma-4

Interactions

AP4B1 has been shown to interact with AP4M1.

Clinical relevance

AP4-complex-mediated trafficking plays a crucial role in brain development and functioning.