Acetic formic anhydride


Acetic formic anhydride is an organic compound with the chemical formula and a structural formula of --O-H. It can be viewed as the mixed anhydride of acetic acid and formic acid.

Preparation

Acetic formic anhydride can be produced by reacting sodium formate with acetyl chloride in anhydrous diethyl ether between 23–27 °C.
It can also be prepared by the reaction of acetic anhydride and formic acid at 0 °C.

Applications

Acetic formic anhydride is a formylation agent for amines, amino acids, and alcohols. It is also a starting material for other compounds such as formyl fluoride.
Acetic formic anhydride is used in the synthesis of quazodine.