Adenosylcobyric acid synthase (glutamine-hydrolysing)
In enzymology, an adenosylcobyric acid synthase is an enzyme that catalyzes the chemical reaction
The four substrates of this enzyme are ATP, adenosylcobyrinic acid a,c-diamide, L-glutamine, and H2O; its four products are ADP, phosphate, adenosylcobyric acid, and L-glutamate.
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with glutamine as amido-N-donor. The systematic name of this enzyme class is adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase . Other names in common use include CobQ, cobyric acid synthase, 5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine, amido-ligase, and Ado-cobyric acid synthase . This enzyme is part of the biosynthetic pathway to cobalamin in bacteria.
