After graduation, Eustace worked briefly for Silicon Solutions, a startup in Silicon Valley, before joining Digital, Compaq and then HP's Western Research Laboratory, where he worked 15 years on pocket computing, chip multi-processors, power and energy management, internet performance, and frequency and voltage scaling. In the mid-1990s, he worked with Amitabh Srivastava on ATOM, a binary-code instrumentation system that forms the basis for a wide variety of program analysis and computer architecture analysis tools. These tools had a profound influence on the EV5, EV6 and EV7 chip designs. Eustace was appointed head of the laboratory in 1999, but left it three years later to join Google, then a four-year-old startup. At Google, he worked as Senior Vice President of Engineering until he retired from that section of Google on March 27, 2015. In the course of his professional career, Eustace co-authored nine publications and appeared as co-inventor in ten patents.
Stratosphere jump
In 2011, Eustace decided to pursue a stratosphere jump and met with Taber MacCallum, one of the founding members of Biosphere 2, to begin preparations for the project. Over the next three years, the Paragon Space Development technical team designed and redesigned many of the components of his parachute and life-support system. On October 24, 2014, Eustace made a jump from the stratosphere, breaking Felix Baumgartner's 2012 world record. The launch-point for his jump was from an abandoned runway in Roswell, New Mexico, where he began his gas balloon-powered ascent early that morning. He reached a reported maximum altitude of, but the final number submitted to the World Air Sports Federation was. The balloon used for the feat was manufactured by the Balloon Facility of the Tata Institute of Fundamental Research, Hyderabad, India. Eustace in his pressure suit hung tethered under the balloon, without the kind of capsule used by Felix Baumgartner. Eustace started his fall by using an explosive device to separate from the helium balloon. His descent to Earth lasted 4 minutes and 27 seconds and stretched nearly with peak speeds exceeding, setting new world records for the highest free-fall jump and total free-fall distance. However, because Eustace's jump involved a drogue parachute, while Baumgartner's did not, their vertical speed and free-fall distance records remain in different categories. Unlike Baumgartner, Eustace, a twin-engine-jet pilot, was not widely known as a daredevil prior to his jump. Eustace's world record jump was featured in two episodes of STEM in 30, a television show geared towards middle-school students by the National Air and Space Museum.