Benjamin holds a certificate in obstetrics and gynecology from the Royal College of Physicians and Surgeons of Canada and a certificate from the College of Physicians and Surgeons of Quebec. She became a Fellow of the American College of Obstetrics and Gynecology in 1981. A consultant with Prince Edward CountyMemorial Hospital in Ontario from 1978 to 1979, Benjamin joined the Department of Gynecology and Obstetrics at the Royal Victoria Hospital in Montreal in 1979. She belongs to the perinatal unit and is associate professor at McGill University. Benjamin established and became director of the Royal Victoria Hospital's Antenatal Day Center in 1979. She focuses on high-risk pregnancies and works with a multidisciplinary team that supports treatment that avoids hospitalization, so that patients can remain with their families - a first in North America. In her career as a physician, Dr. Benjamin has overseen and cared for a number of high-risk pregnancies with successful outcomes for mothers and babies. She performed Canada's first successful diabetic renal transplant and pregnancy, and Canada's first interval delivery of twins, who were delivered six weeks apart with both babies surviving in full health. She also oversaw Quebec's first peritoneal dialysis pregnancy and delivery in 1994, and its first successful pregnant peritoneal dialysis on cycler in 2003. She also delivered the first infant whose cord blood stem cells were used for a bone-marrow transplant to cure the mother's leukemia, resulting in full health for both infant and mother in 2001. Benjamin was one of four specialists who sued McGill University Health Centre over medical quotas. Benjamin pursues many philanthropic endeavours, supporting children through the World Vision child sponsorship programme, and support for the Samaritan's Purse, The Salvation Army and LIFE Outreach International.
Dr. Alice Benjamin Leadership Award established by Chaya and Lorne Lieberman to recognize leadership in the Department of Obstetrics and Gynecology's residency program
Dr. Alice Benjamin Global Maternal and Child Health Awards established in 2018 in honour of Dr. Benjamin by friends, family, and patients whose lives she touched throughout her career. Provides support to students or trainees undertaking electives or research projects overseas in under-resourced areas of the world.
