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Allopurinol hypersensitivity syndrome
Allopurinol
hypersensitivity
syndrome
typically occurs in persons with preexisting
kidney failure
.
Weeks
to months after
allopurinol
is
begun
, the
patient
develops a
morbilliform eruption
or, less commonly, develops one of the far more
serious
and
potentially
lethal
severe cutaneous adverse reactions
viz
., the
DRESS syndrome
,
Stevens Johnson syndrome
, or
toxic epidermal necrolysis
.