Anemic galaxies not only show spiral arms of low contrast but also a low content and density of neutral hydrogen, redder colours than a normal spiral, fewer H II regions, and thus a low star formation activity. At first it was believed their molecular hydrogen content was similar to that of a normal spiral, but subsequent studies have shown that a number of them are deficient in molecular gas. Anemic galaxies should not be confused with galaxies with red colors due to a low star formation activity but which show a normal content of neutral gas, as is the case of the Andromeda Galaxy.
Evolution
As most galaxies of this type are present in rich galaxy clusters, it has been proposed that this may be one of the reasons that converts normal spirals into anemic ones. Studies of spiral galaxies in the nearby Virgo cluster have shown not only how, unlike in isolated spiral galaxies, in most cases their neutral gas and star formation are truncated within their optical disks, in some cases quite severely, but also how star formation activity in them is lower than on spirals outside clusters,: this means that processes that take place in galaxy clusters as interactions with the intracluster medium like ram-pressure strippingand/orinteractions with other neighboring galaxies are responsible of the origin of anemic galaxies, stripping the normal spirals of their gas, increasing in some cases their star formation activity, and thus in the end quenching the latter as their gas is exhausted and not replenished. Spiral galaxies may have become anemic ones by exhausting their supply of gas via star formation activity. An anemic galaxy's most probable fate is to lose their remaining gas and star formation, becoming similar to a lenticular galaxy: it therefore is likely that most lenticular galaxies in clusters, are former spiral galaxies.
Passive spiral galaxies
Passive spiral galaxies are a type of spiral galaxy located in rich galaxy clusters at high redshifts that present spiral structure, but little or no star formation, in some cases hidden by dust and concentrated within its innermost regions. Often, they seem too to have few or no massive stars. According to computer simulations, they are systems on the way to becoming a lenticular galaxy as they have lost the hydrogen that is assumed to be present in the haloes of spiral galaxies and that replenishes them with new gas to form stars. While they share at least some properties with anemic galaxies, its relationship with them is unclear: they may be a more advanced stage on the evolution of a spiral galaxy to become a lenticular than the anemic galaxies or passive spirals and anemic galaxies may be the same type of object, their difference is that the former are much farther away than the latter.