Animal models of epilepsy


Animal models of epilepsy have helped to advance the understanding of how normal brains develop epilepsy, and have been used in pre-clinical trials of antiepileptic drugs. Epilepsy is a set of syndromes which have in common a predisposition to recurrent epileptic seizures. Animal models of epilepsy and seizures can be divided into three basic categories: genetic animal models, chemically induced models, and electrically induced models. New models are using light-gated ion channels to turn on cell firing and these are part of optogenetic induction models of epilepsy.