Anthera Pharmaceuticals Anthera Pharmaceuticals, Inc. is an American biopharmaceutical company focused on developing and commercializing products to treat serious conditions associated with cystic fibrosis , inflammation and autoimmune diseases . Liprotamase, Anthera’s leading drug candidate which is being developed for exocrine pancreatic insufficiency is currently in Phase 3 clinical trials , and A-623 for the treatment of IgA nephropathy is currently in Phase 2 clinical trial .Products Blisibimod is a selective peptibody antagonist of B-cell activating factor . BAFF is critical to the development , maintenance and survival of B-cells, but is known to be up-regulated in autoimmune diseases. It is primarily expressed by macrophages , monocytes and dendritic cells . Blisibimod binds to BAFF and inhibits the interaction of BAFF with its receptors. Blisibimod is currently being evaluated in IgA nephropathy .Sollpura July 2014 , Anthera acquired Sollpura from Eli Lilly and Company . Sollpura is an investigational pancreatic enzyme replacement therapy that uses three biotechnology-derived digestive enzymes intended to treat patients with endocrine pancreatic insufficiency as a result of cystic fibrosis and other diseases.
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