Born in Mechelen, Limbombe began his youth career with Mechelen in 2000. In 2005, he joined Belgian Pro League side Racing Genk. He made his first team debut at the age of 16 in a 3–1 victory at Lokeren on 18 September 2010. He also played for Genk in the Champions League and the UEFA Europa League. During his career with Racing Genk he won the Belgian Pro League in 2010–11 season, and he also won the Belgian Super Cup in 2011, in total he scored 2 goals in 62 League appearances. For the second half of the 2013–14 season, Limbombe was sent on loan to Lierse SK where he scored 2 goals in 7 games.
NEC Nijmegen
On 30 August 2014, he signed with Eerste Divisie side N.E.C on a three-year deal with the option of a fourth year. He impressed in his first season at the club, scoring 14 goals and providing numerous assists in his debut season at the club, helping N.E.C. win the Eerste Divisie as champions and gain promotion to Eredivisie. On 12 August 2015, Limbombe played for N.E.C. against Excelsior in the opening day of the 2015–16 Eredivisie season in a 1–0 victory. A day later, NEC rejected a £1.5 million bid from English side Leeds United for Limbombe. On 22 August, the club announced that Limbombe had been left out of the squad against Ajax due to deeming him 'insufficiently focused' after the interest linking him with Leeds United. However, on 1 September, Leeds ended their interest in Limbombe after failing to up the bid, signing winger Jordan Botaka from Dutch Club Excelsior instead. After impressing during the 2015–16 season, scoring 7 goals and gaining 7 assists in the Eredivisie, on 1 June 2016, Limbombe amid further interest again from English side Leeds United, handed in a transfer request at NEC. However, Leeds were again unable to agree on a fee with N.E.C for the player.
On 26 June 2019, Limbombe joined Belgian side Standard Liège on a one-year loan. His new club secured an option to sign him permanently. After scoring in his first match for the club, he suffered a knee injury in October. In December 2019, it was announced that Limbombe's loan at Standard Liège would be cut short and that he would return to Nantes in January.
International career
Limbombe was born in Belgium to Congolese parents, and is eligible to represent either nation. He represented Belgium at U16 international level and has played at Belgium U17 level. In 2012, he was capped for Belgium U19's. He was named in the Roberto Martinez Belgian squad for the friendly against Saudi Arabia in Brussels on 27 March. He made his debut in a 4-0 win against Saudi Arabia, as he was subbed in at half-time.