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Antibody-oligonucleotide conjugate
Antibody-oligonucleotide
conjugates
or
AOCs
belong
to
a class
of
chimeric
molecules
combining
in their
structure
two important
families
of biomolecules:
monoclonal antibodies
and
oligonucleotides
.
Combination
of
exceptional
targeting
capabilities
of
monoclonal
antibodies
with
numerous
functional
modalities
of oligonucleotides has been fruitful for a
variety
of
applications
with
AOC
including
imaging
,
detection
and
targeted therapeutics
.
