Antonie Marinus Harthoorn, or 'Toni' Harthoorn was a veterinarian and environmentalist known for his role in the development of large-animal tranquilizers and their impact on the conservation movement. Additionally, Harthoorn's animal sanctuary was the inspiration for the television seriesDaktari.
After his Ph.D., Harthoorn went initially to Uganda, then to Kenya and Tanzania. There he studied the effects of various sedative drugs on wild African mammals and with a team invented the M-99 capture drug and refined the tranquilliser gun, or 'Capture gun', for darting animals. This was a breakthrough in animal transport, enabling the safe movement of rare animals to game sanctuaries from places in which they were at risk from poaching or urban development. The research effort and its eventual triumph is recorded in Dr Harthoorn's first book: The Flying Syringe. Capture gun technology is today used extensively in wildlife reserves, urban animal management, criminal human capture and zoological gardens. Before the invention of this technology animals were usually caught manually by being rounded up, penned, and transported without sedation, resulting in the death from stress of many hundreds of animals. In the 1960s, the Hungarian-born American film and TV producerIvan Tors came to Kenya on holiday and visited an animal orphanage set up by Dr Harthoorn and his wife, Sue Hart. Tors was so impressed by the idea that he developed a TV series named Daktari which ran worldwide for several decades. The name has persisted in the 21st century in various forms in the names of several trademarked drugs. The animal characters from this series, Clarence the cross-eyed lion and Judy the chimpanzee, are still fondly remembered. The Kenyan experience is recorded in Sue Hart's book Life with Daktari. With Kenyan independence Dr Harthoorn's position as senior lecturer at the veterinary college in Nairobi was abruptly terminated. He moved to South Africa and continued his work with large African mammals, including elephant and rhinoceros transport. His work was absolutely vital in the creation of many South African game reserves, in particular the Hluhluwe–iMfolozi Park reserve in northern Kwazulu-Natal, where his work with Ian Player was vital in preserving the white rhinoceros. He also had a vital role in the saving of thousands of animals marooned on small islands created by the rising waters of the newly formed Kariba Dam in 1959-1960 in Southern Rhodesia. The campaign to save the animals was dubbed Operation Noah. Harthoorn was also a naturopath and homoeopath. He lived near Pretoria, South Africa, with his extended family, and continued to work lifelong in environmental preservation.