Appleton (surname)
Appleton is an Anglo-Saxon locational surname.
- Alistair Appleton, British television presenter
- Charles Appleton , Oxford don and scholarly entrepreneur
- Charles Appleton , English amateur cricketer
- Charles William Appleton, vice president of the General Electric Company, judge and Assistant District Attorney in New York City
- Colin Appleton, footballer
- Daniel Appleton, American publisher, 1800s founder of D. Appleton & Company
- Edward Victor Appleton, English physicist, known for his research on the ionosphere
- Edwin Nelson Appleton, American Medal of Honor recipient
- Francis R. Appleton, lawyer and member of the 400 during the Gilded Age
- George Swett Appleton, American publisher
- Henry Appleton, English captain in the navy and commodore
- James Appleton, American abolitionist
- Jean Appleton, Australian painter, art teacher and printmaker
- John Appleton, American diplomat, politician, and newspaper editor
- John Appleton, Master of University College, Oxford, England
- John E. C. Appleton, Australian theatre and radio producer
- John F. Appleton, American Civil War general from Maine
- John Howard Appleton, American chemist
- John James Appleton, diplomat for the United States
- Jon Appleton, American composer, author and professor of music
- Larry Appleton, a character from the TV series Perfect Strangers
- Michael Appleton, footballer
- Mike Appleton, British television producer
- Natalie Appleton, British/Canadian singer
- Nathan Appleton, American merchant and politician
- Nicole Appleton, British/Canadian singer
- Ray Appleton, American jazz drummer
- Ruel Ross Appleton, campaign manager for Mayor Gaynor of New York City
- Samuel Appleton, an American merchant and philanthropist
- Scott Appleton, American football player
- Stevie Appleton, British singer
- Thomas Gold Appleton, American author and artist
- Victor Appleton, a house pseudonym, famous for the Tom Swift series
- William Appleton , congressman from Massachusetts
- Will Appleton, mayor of Wellington, New Zealand
- William Sumner Appleton, founder of the Society for the Preservation of New England Antiquities
- William M. Appleton, Pennsylvania politician
- William Henry Appleton, American publisher
- William Appleton , American entrepreneur and technologist
- William H. Appleton, American soldier and Medal of Honor recipient
- William Thomas Appleton, Australian businessman, shipping agent and public servant