Arshad Sami Khan was born in January 1942 into an ethnic Pashtun family that had migrated from Afghanistan. He was born to Abdul Sami Khan who served as a Deputy Inspector General of Police. His paternal grandfather, General Mehfooz Jan hailed from Herat, Afghanistan and was the governor of 4 provinces in Afghanistan, namely Herat, Kabul, Jalalabad and Balkh, under the Reign of King Amanullah Khan. Khan's paternal great-grandfather General Ahmed Jan was the civil and military adviser as well as the physician to King Ameer Abdur Rahman Khan. General Ahmed Jan, the father of Gen. Mafooz Jan, was the conqueror of Kafiristan and named it Nuristan. However, at the time of the famous Bacha Saqqaw/Habibullah Kaqani revolution in Afghanistan that Khan's paternal grandfather, General Mehfooz Jan was executed, and as a result the family had to migrate to Peshawar which was a part of British India at that time.
Khan decided in his early years to follow the military traditions of his forefathers and joined the Pakistan Air Force. He became a national hero and was awarded the Sitara-e-Jurat, Pakistan's third highest military medal of honour for bravery. His name is honoured at the Pakistan Air Force Museum in Karachi. He was also the youngest recipient of the prestigious "Best Fighter Pilot's Trophy". Khan also had the distinction of serving three Presidents of Pakistan as their Aide-de-camp ; namely presidents Ayub Khan, Yahya Khan and Zulfiqar Ali Bhutto. He retired from the Air Force in 1972 and joined the Foreign Service on the behest of President Zulfiqar Ali Bhutto.
Khan wrote a book about his experience as an Aide-de-camp entitled "Three presidents and an Aide" which was released in March 2008 and went on to become a best-seller in South Asia. The book is a candid eyewitness account of historical events, seen from within the 'ring-side' that occurred during the reign of the 3 presidents- Presidents Ayub Khan, Yahya Khan and Zulfiqar Ali Bhutto. No Publisher in Pakistan was willing to publish the book. It was therefore published and released in India, launched by former Indian Prime Minister I.K. Gujral to rave reviews and sales.
Illness
Khan was diagnosed with pancreatic cancer in 1989. Prime Minister Benazir Bhutto had him flown to London where he was operated at Cromwell Hospital. However, within 3 months of the operation thereafter, he resumed working in the Foreign Office continuing his Ambassadorial Assignments around the world, whilst battling cancer for 20 years. He died on 22 June 2009 at 'Kokilaben Dhirubhai Ambani' Hospital in Mumbai. His burial ceremony took place in Islamabad with profound Military Honours including a 21-Gun Salute.