BATF (gene)
Basic leucine zipper transcription factor, ATF-like, also known as BATF, is a protein which in humans is encoded by the BATF gene.Function
The protein encoded by this gene is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events.
Mice without the BATF gene lacked a type of inflammatory immune cell and were resistant to conditions that normally induces an autoimmune condition similar to multiple sclerosis.Interactions
BATF has been shown to interact with IFI35.
