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BBS4
Bardet–Biedl syndrome
4
is a
protein
that in
humans
is
encoded
by the
BBS4
gene
.
This gene encodes a protein which
contains
tetratricopeptide repeats
, similar to
O-linked N-acetylglucosamine transferase
.
Mutations
in this gene have been
observed
in
patients
with Bardet–Biedl
syndrome
type 4
. The encoded protein may
play
a role in
pigmentary retinopathy
,
obesity
,
polydactyly
,
renal
malformation
and
mental retardation
.
Interactions
BBS4 has been
shown
to
interact
with
DCTN1
.