BFSP1
BFSP1 is a gene that encodes the protein filensin in humans.
More than 99% of the vertebrate ocular lens is made up of terminally differentiated lens fiber cells. Two lens-specific intermediate filament proteins, phakinin and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament.
The two BFSP proteins are put into a "type VI" of intermediate filament classification. Unlike other IFs that form unbranched links, the two proteins form a network of filaments together with CRYAA.
