The origin of the name Bagram is not clear, with several theories proposed to describe its origins. Kapisa, an ancient site near the town, is known to be the location of a city once ruled by the Indo-Iranian Kamboja dynasty. - Afghan National Museum.. While the Diadochi were warring amongst themselves, the Mauryan Empire was developing in the northern part of the Indian subcontinent. The founder of the empire, Chandragupta Maurya, confronted a Macedonian invasion force led by Seleucus I in 305 BC and following a brief conflict, an agreement was reached as Seleucus ceded Gandhara and Arachosia and areas south of Bagram to the Mauryans. During the 120 years of the Mauryans in southern Afghanistan, Buddhism was introduced and eventually become a major religion alongside Zoroastrianism and local pagan beliefs. The ancient Grand Trunk Road was built linking what is now Kabul to various cities in the Punjab and the Gangetic Plain. Commerce, art, and architecture developed during this period. It reached its high point under Emperor Ashoka whose edicts, roads, and rest stops were found throughout the subcontinent. Although the vast majority of them throughout the subcontinent were written in Prakrit, Afghanistan is notable for the inclusion of 2 Greek and Aramaic ones alongside the court language of the Mauryans. The last ruler in the region was probably Subhagasena. Bagram became the capital of the Kushan Empire in the 1st century, from here they invaded and conquered Peshawar in the south. The "Bagram treasure" as it has been called, is indicative of intense commercial exchanges between all the cultural centers of the classical time, with the Kushan empire at the junction of the land and sea trade between the east and west. However, the works of art found in Bagram, such as the Begram ivories, are either quite purely Hellenistic, Roman, Chinese or Indian, with only little indications of the cultural syncretism found in Greco-Buddhist art.
Bagram hosts the strategic Bagram Airfield, from which most US air activity in Afghanistan takes place. The runway was built in 1976, and it was a Sovietair base from 1979 to 1989. There is also a Provincial Reconstruction Team which is led by the US. Bagram is also the location of the Parwan Detention Facility; this detention facility was the last prison in Afghanistan under management of the US. It was handed back to the Afghan government on 25 March 2013. The detention centre had earlier come into the attention of the news media as it was claimed that prisoners were tortured. At the time of the hand-over of the facility, human-rights groups like Amnesty International have raised concerns about the treatment of prisoners there. On December 21, 2015, Bagram was the site of a suicide bombing killing 6 people.