Tom Tucker reports on the news about an earthquake that struck Haiti. After seeing the news, Lois organizes a blood drive. Peter was reluctant to give blood until he notices that by doing so he would receive cookies that Lois had made using one of her grandmother's recipes. Peter enjoys the cookie so much he encourages her to open a cookie store together. Going to the bank to get a loan, their cookies win over the bank manager Cookie Monster, who gives the loan officer the approval to let Peter and Lois open a cookie shop. After acquiring a shop they call "Peter's Wife's Cookies," they find that business is not as steady as they had hoped. Meanwhile, Stewie has trouble sleeping when Lois is not around to tell him a bedtime story and not even the Sandman can get him to sleep. To remedy this, Brian slips him some prescription-strength cough medicine so the alcohol will help him. However, Stewie becomes drunk from abusing the medicine and starts acting ridiculously. At the Drunken Clam, Peter asks Quagmire, Cleveland, and Joe on how to improve the cookie shop. Taking Quagmire's advice that "sex sells", Lois finds that Peter has employed bikini beauties to work the shop as Lois is introduced to Cookie, Sugar, Spice, Cinnamon, Brown Sugar, and Butter. Lois is upset until she finds that the idea has made a lot of money and reluctantly agrees to go along with it. Peter takes the stunt to the extreme by turning the cookie store into a strip club, which crosses the line for Lois and she quits. Stewie gets into a drunken Big Wheel accident and injures another child. The next day, he arrives home to find Brian and his toys have arranged an intervention after he nearly killed another kid. After successfully taking care of Stewie, Brian has to break up a masturbation intervention he held for Chris because all his friends were sitting in a circle. An apologetic Peter arrives home and admits he was wrong. He also brings Lois a personalized cookie as well. Peter suggests that they not eat it since Butter helped and she has chlamydia in her fingers. In the news, Tom Tucker announces that the donation of blood that Lois had donated had been incinerated in a gas station by an explosion. After seeing bad luck, Lois tells Peter that they should go back to work to get money for the blood bank, but Peter tells him that he had sold it. The final scene shows Cookie Monster at the cookie shop nibbling on Cookie's breasts.
Production
This is the final episode to be written by longtime executive producer and writer Mark Hentemann who left the series after completion of this episode to work on his own series Bordertown. In a cutaway, Peter eats the hair of Connie Britton, who voices herself. Family Guy executive producer Steve Callaghan said "Especially if you saw her in Friday Night Lights, her hair just looks so yummy, you want to take a bite of it."
Reception
The episode received an audience of 4.74 million, making it the fourth-most watched show on Fox that night, after The OT, The Simpsons and Brooklyn Nine-Nine.
