After the Greek army fled to Karitena, Ibrahim's forces captured Tripolitsa, which was completely abandoned. Immediately afterwards, Ibrahim sent 5,000 soldiers to the plains of Argos in order to seize Nafplion. When Ibrahim's forces reached the mills of Lerna on June 24, Captain Makrygiannis and Minister of War Metaxas organized a resistance force containing 350 Greek soldiers. General Demetrios Ypsilantis, Konstantinos Mavromichalis, Panagiotis Rodios and several philhellenes volunteered in the defense of the garrison. The position was weak and they were very few compared to Ibrahim's army. Thus many were eager to leave using their horses or by fish boats but Makriyannis made sure all horses and fish boats were gone in secret. This made everybody more resolute in defending the position and they started digging trenches. Admiral De Rigny watched from aboard the helplessness of the Greeks and advised Makriyannis against defending the position but Makriyannis ignored him by saying: "They are many indeed but we few have decided to die and have God on our side... And when the few decide to die, most times win... And if we die today we will die for our country and our religion and this death is a good one". "Tres bien" replied De Rigny.
Battle
The battle began at June 24th 1825. Protecting Lerna was vital since the mills contained large quantities of grain that supplied food to Nafplion. The mills of Lerna were surrounded by a stone wall that was flanked by a deep pond and a marsh. Moreover, the garrison was supported by two gunboats that were anchored a short distance from the shore. Unfortunately, the Greeks did not repair a small break inthe stone wall. As a result, a small contingent of Arabs exploited this weakness in the defensive structure and attempted to create an entrance by increasing the size of the break. When the Arabs forced themselves through the break, they were prevented from regrouping once they entered the courtyard. Thirteen Arabs were killed by a charge of Greeks and philhellenes led by Makrygiannis. Ultimately, the remaining Arabs in the overall contingent were forced to flee. The Greeks, afterwards, attempted to fill in the gap in the stone wall. Same time, 50 warriors under the command of Mitros Liakopoulos arrived at the battle to help the defenders. Despite the constant reinforcements he received, Ibrahim was aware of the fact that the Greeks were prepared to staunchly defend the Lerna Mills and he eventually retreated to the plains of Argos. From there, Ibrahim took his army to Tripolitsa on June 29, 1825. The Egyptian casualties, according to Sp. Trikoupis, reached 50 dead men. As long as the Egyptian forces were repelled successfully, some Frenchnaval officers came ashore and congratulate Makriyannis. He was indeed that day the heart of the defenders in Myloi and he was eager to help wherever there was need. Thus he was shot in the right hand from musket fire but kept it secret until the end of the battle. He claims he was recognized by some of Ibrahim's shooters that remembered him from Neokastro. He was taken to the French frigate of Admiral De Rigny to be treated afterwards.