Fowler attended Detroit Country Day School, where he was named to SuperPrep and PrepStar's All-Midwest Teams. He was also listed among the Midwest's top prospects by SuperPrep at No. 72, he was also rated among the nations top wide receivers by Scouts, Inc. at No. 80. He was also ranked among the state's top seniors by the Lansing State Journal at No. 15 overall, Rivals.com at No. 15 also, The Detroit News at No. 16, and the Detroit Free Press at No. 16. He was also named to the Detroit Free Press All-State Division 4 Team. He was also named All-State honorable mention as an all-purpose player by the Associated Press. He was also selected to the All-County Dream Team by The Oakland Press and All-North Team by The Detroit News. As a junior in 2007, Fowler missed five games during the season with a broken collarbone. For the season, he recorded 12 receptions for 265 yards and four touchdowns. As a senior in 2008, he accounted for a total of 1,478 all-purpose yards and 15 touchdowns. He recorded 32 receptions for 683 yards and six touchdowns. On defense, he recorded 16 tackles, three sacks, and three pass-break ups while returning five punts for 218 yards and five kickoffs for 122 yards. In his high school career, Fowler recorded 44 receptions for 903 yards and 10 touchdowns, he also rushed the ball 58 times for 542 yards and nine touchdowns. In addition to playing football, Fowler won the Oakland County 100-meter and state long jump titles in 2008. He was also a member of the Detroit Country Day School Yellow Jackets' 2007 state championship basketball team.
College career
After graduating from high school, Fowler attended Michigan State where he majored in economics. As a freshman in 2009, Fowler redshirted with a stress fracture in his foot. As a redshirt freshman, in 2010, he appeared in all 13 games and finished sixth on the team with 573 all-purpose yards. He recorded 14 receptions for 175 yards, and carried the ball seven times for 62 yards. He also returned 15 kickoffs for 336 yards. His return yards ranked second on the team behind Keshawn Martin. Fowler also recorded a career best 161 all-purpose yards against No. 15 Alabama in the 2011 Capital One Bowl. As a redshirt sophomore in 2011, he appeared in just five games due to a foot injury. He recorded two receptions for 20 yards and one carry for six yards. As a redshirt junior in 2012, he led the team with 524 receiving yards and four touchdowns and ranked second with 41 receptions. He also tied for the lead the team with seven receptions of 20-plus yards. As a redshirt senior in 2013, he again led the team in receiving yards, with 622 yards, and touchdowns, with six. He also ranked third on the team with 36 receptions. He finished second on the team with 10 receptions for 20-plus yards. Fowler's six touchdowns ranked sixth in the Big Ten in 2013.
Career statistics
Professional career
Denver Broncos
2014 season
On May 10, 2014, the Denver Broncos signed Fowler to as an undrafted free agent to a one-year, $114,000 contract. On August 30, 2014, he was waived by the Broncos as part of their final roster cuts. On August 31, 2014, he was signed to the practice squad.
On January 15, 2015, the Denver Broncos signed Fowler to a one-year, $550,000 reserve/future contract. Fowler played in all 16 regular season games for the Broncos, ending the 2015 season with 16 receptions for 203 yards. On February 7, 2016, Fowler was part of the Broncos team that won Super Bowl 50. In the game, the Broncos defeated the Carolina Panthers by a score of 24–10. During the game, he caught a two-point conversion from quarterback Peyton Manning to make it a 14-point game late in the fourth quarter. On April 15, 2016, Fowler re-signed with the Broncos.
2016 season
With Trevor Siemian as his new quarterback, Fowler recorded 11 receptions for 145 yards and two touchdowns in the 2016 season.
2017 season
On September 11, 2017, in the season opener against the Los Angeles Chargers on Monday Night Football, Fowler recorded a career-high two receiving touchdowns. He finished the season with a career-high 29 receptions for 350 yards and three touchdowns.
On October 16, 2018, Fowler was signed by the New York Giants. He scored his first touchdown with the Giants in Week 14 against the Washington Redskins in a 40-16 victory. On March 19, 2019, Fowler re-signed with the Giants. He was released on October 1, 2019 as fellow wide receiver Golden Tate was activated following suspension. He was re-signed on October 14, 2019. He was released on November 26.
