Bernstorffsgade and the two parallel streets Reventlowsgade and Colbjørnsensgade were established in 1881. The three streets were named after Andreas Peter Bernstorff, Christian Ditlev Frederik Reventlow and Christian Colbjørnsen, three of the driving forces behind the peasant reforms of the 1780s. The section from Tietgensgade to Kalvebod Brygge was originally called Tømmerpladsgade but it was merged into Bernstorffsgade in 1914. , the site was still dominated by open land, although Tivoli Gardens had opened at the site in 1843. Copenhagen's first railway station opened at an adjacent site in 1847 but had moved to the other side of Vesterbrogade in 1866.
Skandinavisk Panoptikon, a combination of a wax museum and a cabinet of curiosities established by Vilhelm Pacht, opened at the corner with Vesterbrogade in 1885. Cyclisten, a cycling club, constructed a 350 metres long cycle-racing track with canted curves, tribunes and restaurant at the street in 1893. The cycle racing track was inaugurated on 22 May and was used for six-hour races for both men and women. It was joined by CopenhagenGoods Station in 1895-1901. The station was designed by DSB's head architect Heinrich Wenck. The cycle-racing track was torn down in 1904 to make way for the new Central Station which opened in 1911. Bernstorffsgade was originally located a little further to the west but was moved in connection with the construction of the new station.
Notable buildings and structures
The block between Vesterbrogade and Tietgensgade is dominated by Copenhagen Central Station on one side and Tivoli Gardens on the other. The central Station was designed by Heinrich Wenck in the Historicist style. The Panopticon Building was replaced by a new headquarters for Arbejdernes Landsbank in 1954. Tivoli Gardens has one of its two entrances opposite the Central Station. Next to it is the entrance to the Nimb Complex, featuring Nimb Hotel as well as a Hans Christian Andersen Bakery. The Tivoli Corner, designed by Pei Cobb Freed & Partners, is currently under construction at the corner with Vesterbrogade. It wil contain new rooms for Hotel Nimb, a food court, restaurants and shops. Copenhagen Central Post Building, located on the other side of Tietgensgade, was built at the same time as the Central Station and also with Wenck as architect. It was later expanded with a large post terminal in the 1960s. The whole site was sold in 2016. The old Central Post Building will be turned into an upscale hotel while the rest of the area will be cleared to make room for a mixed-use development with offices, hotel and apartments. The project is designed by Lundgaard & Tranberg and comprises several highrises of up to 120 metres. Lundgaard & Tranberg has also designed SEB Bank's tweo buildings at the corner with Kalvebod Brygge. Across the street from the Central Mail Building is the former Western Power Station. Inaugurated by Københavns Belysningsvæsen in 1898, it was the second power station to be built in Copenhagen. The Historicist building was designed by city architectLudvig Fenger and features a turret topped by a large lantern at the corner. The disused plant has been converted into a district cooling plant and administration office for HOFOR, Greater Copenhagen’s largest utility company. 's building Bernstorffsgade 21 is the former home of The Church Association for the Inner Mission in Denmark. The building is from 1916 and was designed by Arthur Wittmaack. It is now used by Copenhagen Municipality. The neighboring building at No. 23. was designed by Albert Oppenheim. The next building, which fronts Polititorvet, was completed for the insurance company Arbejdsgivernes Ulykkesforsikring in 1914 to design by Knud Arne Petersen. Rigspolitiet is now based in the building. The building on the other side of Polititorvet is the headquarters of Falck.