Wilson started college at Jersey City State College at age 31, after her youngest child began school. She worked as a high schoolhistory teacher at Governor Livingston Regional High School and was active in the League of Women Voters before running for office. In 1971, Wilson was elected to the Berkeley Heights, New Jersey Township Committee, the first woman to win local office in that municipality. In the Watergate landslide election of 1973, Wilson ran successfully for a seat in the State Assembly. Running with Arnold D'Ambrosa, they defeated two Republican incumbents, Herbert H. Kiehn and Arthur Manner. Wilson was the top vote-getter and ran more than 6,000 votes ahead of the two Republican Assemblymen. As a freshman legislator, Wilson won a leadership post and served as the Assembly Majority Whip. She sought re-election to a second term in 1975, but was unsuccessful. After D'Ambrosa was caught up in a political scandal, she ran with Rahway Democratic Chairman William A. Wolf; they lost to Republicans Donald DiFrancesco, who would later serve as governor, and William J. Maguire, a former Union County Freeholder. Wilson ran 2,387 votes behind DiFrancesco. Following her loss, Governor Brendan Byrne appointed her to serve as Assistant Commissioner of the New Jersey Department of Environmental Protection. From 1980 to 1981, she served in the Carter Administration as Associate Director for Recreational Programs at the U.S. Department of the Interior. She returned to the Byrne Administration from 1981 to 1982 as the Deputy Commissioner of the New Jersey Department of Labor and Industry. Governor James McGreevey appointed her to serve on the New Jersey Pinelands Commission in 2002. In 2005, Governor Richard Codey named her Chairman. She was the founder of the Center for Non-Profit Corporations, which is a consulting firm, and a toxic-waste cleanup company. She held that post until 2008. Wilson, who grew up in Burlington and returned there in later years, has also served as Chair of the Burlington City Historic Preservation Commission, as Trustee of the Pinelands Preservation Alliance, as Trustee of the Whitesbog Preservation Trust, and as Trustee of Family Service of Burlington.