Blister beetle Blister beetles are beetles of the family Meloidae , so called for their defensive secretion of a blistering agent , cantharidin . About 7,500 species are known worldwide. Many are conspicuous and some are aposematically colored, announcing their toxicity to would-be predators.Description Blister beetles are hypermetamorphic , going through several larval stages, the first of which is typically a mobile triungulin . The larvae are insectivorous , mainly attacking bees, though a few feed on grasshopper eggs. While sometimes considered parasitoids, in general , the meloid larva apparently consumes the immature host along with its provisions , and can often survive on the provisions alone; thus it is not an obligatory parasitoid , but rather a facultative parasitoid, or simply a kleptoparasite . The adults sometimes feed on flowers and leaves of plants of such diverse families as the Amaranthaceae , Asteraceae , Fabaceae , and Solanaceae . Cantharidin, a poisonous chemical that causes blistering of the skin, is secreted as a defensive agent. It is used medically to remove warts and is collected for this purpose from species of the genera Mylabris and Lytta , especially Lytta vesicatoria , better known as "Spanish fly".Toxicity Cantharidin is the principal irritant in "Spanish fly", a folk medicine prepared from dried beetles in the family Meloidae. The largest genus , Epicauta , contains many species toxic to horses. A few beetles consumed in a single feeding of alfalfa hay may be lethal. In semiarid areas of the western United States , modern harvesting techniques may contribute to cantharidin content in harvested forage. The practice of hay conditioning , crushing the stalks to promote drying, also crushes any beetles present and causes the release of cantharidin into the fodder. Blister beetles are attracted to alfalfa and weeds during bloom. Reducing weeds and timing harvests before and after bloom are sound management practices . Using equipment without hay conditioners may reduce beetle mortality and allow them to escape before baling.Systematics Subfamily Eleticinae Tribe Derideini Anthicoxenus Deridea Iselma Iselmeletica Tribe Morphozonitini Ceriselma Morphozonitis Steniselma Tribe Eleticini Tribe Spasticini Eospasta Protomeloe Spastica Xenospasta Subfamily Meloinae Tribe Cerocomini Anisarthrocera Cerocoma Diaphorocera Rhampholyssa Rhampholyssodes Tribe Epicautini Denierella Epicauta Linsleya Psalydolytta Tribe Eupomphini Cordylospasta Cysteodemus Eupompha Megetra Phodaga Pleropasta Tegrodera can be safely handled, provided the animal is not startled, and allowed to move around freely. Otherwise, painful poisonings may occur. : Note the drop of dark orange defensive fluid on its thorax . Tribe Lyttini Acrolytta Afrolytta Alosimus Berberomeloe Cabalia Dictyolytta Eolydus Epispasta Lagorina Lydomorphus Lydulus Lydus Lytta Lyttolydulus Lyttonyx Megalytta Muzimes Oenas Parameloe Paroenas Physomeloe Prionotolytta Prolytta Pseudosybaris Sybaris Teratolytta Tetraolytta TrichomeloeTribe Meloini Cyaneolytta Lyttomeloe Meloe Spastomeloe SpastonyxTribe Mylabrini Actenodia , one of many known in South Africa as "CMR beetle"Ceroctis Croscherichia Hycleus Lydoceras Mimesthes Mylabris Paractenodia Pseudabris Semenovilia Xanthabris Tribe Pyrotini Bokermannia Brasiliota Denierota Glaphyrolytta Lyttamorpha Picnoseus Pseudopyrota Pyrota Wagneronota Genera incertae sedis Australytta Calydus Gynapteryx Oreomeloe Pseudomeloe Subfamily Nemognathinae Tribe Horiini Tribe Nemognathini Cochliophorus Euzonitis Gnathium Gnathonemula Leptopalpus Megatrachelus Nemognatha Palaestra Palaestrida Pseudozonitis Rhyphonemognatha Stenodera Zonitis Zonitodema Zonitolytta Zonitomorpha Zonitoschema Tribe Sitarini Allendeselazaria Apalus Ctenopus Glasunovia Nyadatus Sitaris Sitarobrachys Stenoria Genera incertae sedis Hornia Onyctenus Sitaromorpha Tricrania Subfamily Tetraonycinae Tribe Tetraonycini Meloetyphlus Opiomeloe Tetraonyx
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