Gale was born to a Jewish family in University City, Missouri, the son of Maxine, née Kippel,, an art dealer and violinist, and Mark R. Gale, an attorney, World War II veteran, and later a University City councilman. He is the oldest of his two other brothers, Charlie, who wrote the screenplay for Ernest Scared Stupid, and Randy. Gale received a B.A. in Cinema in 1973 from the University of Southern California, where he wrote fanzine reviews for classmate Mike Glyer's fanzine, and met classmate Zemeckis. As a teen, he created his own comic book, The Green Vomit, using spirit duplication, and also co-founded a popular comic book club in St. Louis. Later, he and his brother Charlie made his own amateur three-film series parody of the Republic PicturesCommando Cody serials, using the character name "Commando Cus". The last two of these were made in collaboration with Richard Rosenberg.
As screenwriters, Gale and Zemeckis have collaborated on films including 1941, I WannaHold Your Hand, Used Cars, and Trespass, the last set in East St. Louis, Illinois near Gale's home town. Gale and Zemeckis were nominated for an Academy Award for their screenplay for Back to the Future. In 2002, Gale debuted as a feature-film director with Interstate 60: Episodes of the Road. He had previously directed and written the 20-minute theatrical release . He also wrote the novelization for his movie 1941 and helped develop the arcade gameTattoo Assassins. On 31 January 2014, it was announced that a stage musical adaptation of the first Back to the Future film was in production.
Comic books
As a teenager, Bob Gale wrote to Marvel Comics, and a letter to Stan Lee appears in Iron Man #2, published in June 1968. Gale has written for comics, including Marvel Comics'Ant-Man's Big Christmas and DC Comics' Batman. In 2001, Gale had a short run on Marvel Comics' Daredevil, writing issues #20-25 of Volume 2. Working with artists Phil Winslade and David Ross, they created the story arc "Playing to the Camera." Writer-painter David Mack contributed covers to the run. In 2008 Gale worked as one of the writers among the rotating writer/artist teams on The Amazing Spider-Man, which at the time, was published three times a month. His issues included #546, #552-554, #558, #562-564.