The building was converted into shops after the station's 1939 closure and by the late 1960s was occupied by a popular café called 'The Silver Slipper', a nightclub called 'Sgt. Peppers' and a plumbers shop, 'Morton's'. It was ravaged by fire on the night of 22 March 1970.
Destruction by fire
Local Glasgow newspapers, the Evening Times and the Evening Citizen, of 23 March 1970 stated the fire started after a 'Battle of the Bands' contest had been held in the nightclub and it was likely someone had left a cigarette burning in the attic as it was primarily the roof space that had burned resulting in the decision of the Fire Brigade to pull down the two domed towers for safety reasons the following day. The cafe owner's German Shepherd dog died of smoke inhalation but no humans were injured. Despite the outer walls of the building remaining intact and the damage confined largely to the roof area, the decision was taken by the then Glasgow Corporation not to undertake repairs and instead to completely demolish the building. At the time of the fire, plans were being considered to demolish the building as part of a controversial scheme to widen Great Western Road and this might lie behind the decision not to repair the building despite its prominent and recognisable presence in the West End for seventy-four years and its housing of three viable local businesses.
Today
The site of Botanic Gardens Station remains derelict to this day, over forty years after the fire. The platforms still remain underground where they can be seen from above through still open air vents in the Botanic Gardens, and the floor of the building is still visible within the fenced-off section of the gardens marking where it stood. The platforms are accessible via the tunnel portal at the Kirklee end of the Gardens. An abandoned tramway kiosk designed in the same style as the building and built in 1903 is still present at the site. The site is heavily overgrown, vandalised and dilapidated and is considered dangerous to enter.
Redevelopment
In September 2007, it was reported plans were under consideration to redevelop the site as a Bar/Restaurant/Nightclub/Exhibition Space and miniature railway which would involve completely rebuilding the station building to its original design on its footprint. The plans were met with considerable opposition from local people who organised a campaign group largely objecting to the idea of a nightclub appearing in a tranquil place like the Gardens. It was reported on 17 April 2008 that the campaign against the plans had been successful and Glasgow City Council had abandoned the plans. There are no current plans to redevelop the site.