CIR (gene)


Corepressor interacting with RBPJ 1 is a protein that in humans is encoded by the CIR1 gene.

Interactions

CIR has been shown to interact with SNW1.

Model organisms

s have been used in the study of CIR1 function. A conditional knockout mouse line called Cir1tm3aWtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping - in-depth bone and cartilage phenotyping