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CLDN18
Claudin-18
is a
protein
that in
humans
is
encoded
by the
CLDN18
gene. It
belongs to
the group of
claudins
.
CLDN18 belongs to the large
claudin
family of proteins
, which form
tight junction
strands
in
epithelial cells
.
Clinical
significance
Isoform
2 is
abundant
in
gastric
tumors
.
Experimental
antibody
IMAB362
targets
Claudin
18
.2 to help
treat
gastric
cancers
.