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CSP-2503
CSP-2503
is a
potent
and
selective
5-HT
1A
receptor agonist
, 5-HT
2A
receptor antagonist
, and 5-HT
3
receptor
antagonist
of the
phenylpiperazine
class
. First
synthesized
in
2003
, it was
designed
based on
computational models
and
QSAR
studies
. In
rat
studies, CSP-2503 has
demonstrated
anxiolytic
effects
, and thus has been
suggested
as a
treatment
for
anxiety
in
humans
with a
multimodal
mechanism of action
.