Camps quinoline synthesis


The Camps quinoline synthesis is a chemical reaction whereby an o-acylaminoacetophenone is transformed into two different hydroxyquinolines using hydroxide ion.
The relative proportions of the hydroxyquinolines produced are dependent upon the
reaction conditions and structure of the starting material. Although the reaction product is commonly depicted as a quinoline, it is believed that the keto form predominates in both the solid state and in solution, making the compound a quinolone.
An example of the Camps reaction is given below: