Cannabigerolic acid


Cannabigerolic acid is the acidic form of cannabigerol. It is a dihydroxybenzoic acid that is olivetolic acid in which the hydrogen at position 3 is substituted by a geranyl group. A biosynthetic precursor to Delta-tetrahydrocannabinol, the principal psychoactive constituent of the Cannabis plant. It is a dihydroxybenzoic acid, a diterpenoid, a polyketide, a member of resorcinols and a phytocannabinoid. It derives from an olivetolic acid. It is a conjugate acid of a cannabigerolate.
In the Cannabis plant, olivetolic acid and geranyl diphosphate are synthesized into CBGA. CBGA is converted in the plant by CBCA synthase, cannabidiolic acid synthase and tetrahydrocannabinolic acid synthase into CBCA, CBDA and tetrahydrocannabinolic acid. THCA can be decarboxylated into THC by drying and heating plant material.