Carmelina Negri was born in the May 9, 1910,the daughter of Gaetano Negri and Teresa Galbiati. She was integrated in the Catholic Action movement, in which, through its enormous enthusiasm and eventually influenced by some members of her family, who accompanied her on the growth of living the faith in the spirit of prayer, the love for Jesus in the Eucharist, the devotion to Our Lady and service to the Catholic Church. In 1926, she completed her studies and began work in a bank. She met Giuseppe Carabelli, a virtuous and modest young man whom she married on January 23, 1935. They had both always wanted a large family who could convey the "Good News" of a higher love, like that of God. Within her large family she came to be called by the diminutive and tender name of "Mamma" Carmela. , Italy. In mid-September 1950, Carmela Carabelli made a trip to the convent of San Giovanni Rotondo where she met the supposedly stigmatized Capuchin friar and priestPadre Pio of Pietrelcina. She defined this trip as being "memorable" and it further increased her love for prayer and desire to do good. Carabelli became soon after one of Padre Pio's spiritual daughters. In January 1957, the first signs of disease were seen in her husband. In March 1959, Giuseppe Carabelli died. The Archbishop of Milan, Cardinal Giovanni Montini pointed out the virtues of this unique and uplifting man, giving him his blessing.
Carabelli in her spiritual writings revealed her interior locutions with Jesus in which He allegedly supplied some mysteries about his life, about God the Father as the father of all mankind; about Our Lady, who in turn will spoke on the person of St. Joseph, among other divine mysteries. Through this privileged personality, Carabelli began to travel the world. Her writings were already translated into major languages and distributed in several countries. In a letter from Monsignor Pietro Santoro, Bishop of Termoli and later Archbishop of Campobasso-Boiano, addressed to the publication Fidelitas on January 9, 1972, he says of the spiritual writings of Carabelli: "These writings are truly rich in faith and holy ardor for the Divine Cause Her books will do much good to humanity that feels increasingly tormented and who lives far from God." In the previous year, he had already granted ecclesiastical approval nihil obstat and imprimatur, certifying Carmela's writings as being in accord with the moral doctrine of the Catholic Church.