Handler's noteworthy achievement is a case considered to be a landmark case that was won on an ironic, yet relatively simple, but critical oversight. At issue were the sale of intellectual property rights to certain Marvel Enterprises characters that Marvel's new owners thought it bought with the company. The claim was successful because, although the purchaser of those rights had a valid signed contract with the former owners of Marvel, the actual new rights were never registered with the United States Copyright Office. Handler's discovery of that fact, and her interpretation of IP law during the court proceedings, caused the rights to revert to Marvel, which was bought by Avi Arad and Ike Perlmutter. Handler has been working with studios to develop a legal licensing system for digital video. Handler argues that the idea of Creative Commons, created by Stanford University professor Larry Lessig, is an "interesting compromise" - allowing for protection for copyrightable interests of the video itself while also acknowledging that the technology being used that causes the video to be accessed online modifies the licensing arrangement. Aside from Handler's experience in motion picture and entertainment licensing, and she has worked with IP issues dealing with energy, pharmaceuticals and medical devices. Among her antitrust work, Handler has represented the National Basketball Association and several of the major motion picture studios defending them against "block booking". In 1998, Handler took on the case of Holocaust rescuer Irene Gut Opdyke when Opdyke tried to re-gain the rights to tell the "authorized" account of her life story, which she had previously assigned in a lawful motion picture option agreement. Handler worked with the parties to reach an agreement and the case was dismissed with prejudice. In an ironic twist, after the trial, all parties agreed that the promoter did "nothing wrong." Opdyke publicly acknowledged the promoter who she sued by thanking him in her book, “In My Hands” and agreed to give him a producer credit for the eventual "authorized" motion picture about her life story. Handler has been a partner at Kaye Scholer LLP., O’Donnell & Shaeffer LLP and Thelen Reid & Priest LLP.
Handler was named one of the "Top 50 Women Litigators in California" by Daily Journal Extra in 2005, 2004, 2003 and 2002. In 2001, and was named one of the "Lawyers of the Year" by California Lawyer.
