Charles, Duke of Guise Charles de Lorraine , 4th Duke of Guise Henry I, Duke of Guise and Catherine of Cleves .Biography He was born in Joinville ,, in the Champagne-Ardenne region of northeastern France . Originally styled the Chevalier de Guise , he succeeded as Duke of Chevreuse upon the death of his great-uncle Charles of Guise , Cardinal of Lorraine , a title he later resigned to his brother Claude .assassination in 1588, he succeeded him as Duke of Guise, but was kept in prison in Tours for three years, escaping in 1591. While the Catholic League had great hopes for him, and considered placing him on the throne, he declared his support for Henry IV of France in 1594, for which Henry paid him four million livres and made him Governor of Provence . In 1595, he captured Marseille from the Duc d'Épernon , who held it for the League .Grand Master of France and Admiral of the Levant.Cardinal Richelieu for siding with Marie de' Medici , he withdrew to Italy in 1631. His wife and younger children joined him in Florence , where the family was protected by the House of Medici . His sons François and Charles Louis died in Italy during these years of exile. Duke Charles himself died, at Cuna , in 1640 . His widow and children were permitted to return to France in 1643.Family On 6 January 1611 he married Henriette Catherine of Joyeuse . They had: François, Prince of Joinville , who died in Florence during the family's exile and was buried in the church of San Lorenzo and later reinterred at Joinville. He was deemed "the most accomplished prince of his day." Twin boys , who were very frail and sickly. They died on the same day. Henry II, Duke of Guise , Archbishop of Reims Marie, Duchess of Guise A girl, called Mademoiselle de Joinville , who was born healthy but caught a cold in the winter of 1617 and died shortly thereafter. Charles Louis and was buried at San Lorenzo and later at Joinville, styled Duke of Joyeuse Françoise Renée, Abbess of Montmartre Louis, Duke of Joyeuse , also Duke of Angoulême Roger called the Chevalier de Joinville and later the Chevalier de Guise , Knight of the Order of Malta , died of fever at Cambrai and buried near his ancestors at Joinville.Ancestry
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