Chlorpropham


Chlorpropham is a plant growth regulator and herbicide used as a sprout suppressant for grass weeds, alfalfa, lima and snap beans, blueberries, cane fruit, carrots, cranberries, ladino clover, garlic, seed grass, onions, spinach, sugar beets, tomatoes, safflower, soybeans, gladioli and woody nursery stock. It is also used to inhibit potato sprouting and for sucker control in tobacco. Chlorpropham is available in emulsifiable concentrate and liquid formulations.
Chlorpropham is within the maximum residue limit regulation in Germany germination inhibitors approved for the treatment of potatoes for the purpose of preservation after harvest. Chlorpropham products are approved as a germination inhibitor for potatoes in Germany, Austria and Switzerland. Chlorpropham is approved for use as a plant regulator and herbicide only on potatoes in the United States.

Uses

When it is used as an Anti Sprouting Agent for potatoes, the formulation is based on HN formulation, Hot Fogging.
For herbicide, an EC formulation is used so that it is dissolvable in water for spray in the field.

Toxicity

Chlorpropham displays a low level toxicity profile, with no signs of acute toxicity after exposure of less than 1000 mg/kg/day. Long term exposure at high doses could cause reduction of body weight gain, decrease in hematocrit and hemoglobin, and increase in blood reticulocytes.
Regarding the carginogenic risk, chlorpropham is classified by the EPA as group E. One of its metabolites is 3-chloroaniline.
The acceptable daily intake ranges from 0.03 mg/kg to 0.05 mg/Kg.

Stability

Chlorpropham is partially degraded in the environment under aerobic conditions and partially hydrolysed in water solution.
A study of the stability of chlorpropham in potatoes revealed that mean concentration of chlorpropham in the tuber decreased spontaneously by 24% and 42% at 28 days and 65 days postapplication respectively. The study also showed that peeling removed 91-98% and washing 33-47%. Residues of chlorpropham were detected in the boiled potatoes, in the boiling water, in the French-fried potatoes and in the frying oil. According to this study, the theoretical dose for a 20 kg infant eating 100g of crude-peeled tuber would be 0.00018 to 0.00342 mg/kg.