Eliopoulos is known as a prolific letterer, in particular for hand-lettering the first 100 issues of the ongoing Savage Dragon series, even after much of the comic book industry had come to rely on computer-generated fonts for dialogue; this was done at Savage Dragon creator Erik Larsen's request; Larsen preferring the individual look of hand-lettered dialogue. He designed the fonts for Marvel Comic's in-house computer lettering unit. He has also contributed lettering work to Valiant Comics, DC Comics, and other publishers. For Dark Horse Comics, Eliopoulos wrote and/or drew some Star Wars stories. Eliopoulous is also known for his comic strip Desperate Times, which showcases art admittedly inspired by the work of Bill Watterson of Calvin and Hobbes fame. Desperate Times features the misadventures of bachelor losers Marty and Toad, which ran as a back-up feature in Savage Dragon, and later Desperate Times comics from Savage Dragon publisher Image Comics and AAArgh! Comics, a part of After Hours Press. Eliopoulos quoted in interview about art inspiration. Following the September 11 attacks, Eliopoulos contributed a story to a Marvel Comics benefit book about how his family was affected by the event, which shares the date of his wedding anniversary. He is the artist and co-writer on Marvel Comics' former back-up feature and current series of one-shot comics, Franklin Richards: Son of a Genius, teamed with writer Marc Sumerak. The first one-shot in the series was nominated for an Eisner Award and a Harvey Award in 2005. Eliopoulos also writes and draws daily webcomics, has contributed cartoon strips to the book series The Complete Idiot's Guide... and to Sports Illustrated. On January 14, 2014 Dial Books published I am Amelia Earhart and I am Abraham Lincoln, the first two books in writer Brad Meltzer's series of children's books, Ordinary PeopleChange the World, which are illustrated by Eliopoulos. Subsequent books released in the series have focused on other historical figures such as Martin Luther King, Jr., Albert Einstein, Rosa Parks, Helen Keller, Lucille Ball, Sacagawea, and Jackie Robinson. Eliopoulos promoted the series during an October 7, 2016 appearance on the NBC talk showLate Night with Seth Meyers, which included a live drawing demonstration in which Meyers participated.
Reception
Doug Zawisza, reviewing the 2011 Fear Itself miniseries for Comic Book Resources, praised Eliopoulos' lettering, singling issue #4 in particular, for which he positively compared Eliopoulous' work to letterer John Workman, to whom Zawisza felt Eliopoulos was paying homage.
