Chromosome 11


Chromosome 11 is one of the 23 pairs of chromosomes in humans. Humans normally have two copies of this chromosome. Chromosome 11 spans about 135 million base pairs and represents between 4 and 4.5 percent of the total DNA in cells. The shorter arm is termed 11p while the longer arm is 11q. At about 21.5 genes per megabase, chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome.
More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single-gene and multi-gene clusters along the chromosome.

Gene

Number of genes

The following are some of the gene count estimates of human chromosome 11. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies. Among various projects, the collaborative consensus coding sequence project takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.
Estimated byProtein-coding genesNon-coding RNA genesPseudogenesSourceRelease date
CCDS1,2242016-09-08
HGNC1,2622716662017-05-12
Ensembl1,3011,0608112017-03-29
UniProt1,3272018-02-28
NCBI1,3148608392017-05-19

Gene list

The following is a partial list of genes on human chromosome 11. For complete list, see the links in the infobox on the right.

Diseases and disorders

The following diseases and disorders are some of those related to genes on chromosome 11:
Chr.ArmBandISCN
start
ISCN
stop
Basepair
start
Basepair
stop
StainDensity
11p15.50230gneg
11p15.4230461gpos50
11p15.3461745gneg
11p15.2745935gpos50
11p15.19351246gneg
11p14.312461490gpos100
11p14.214901545gneg
11p14.115451775gpos75
11p1317752114gneg
11p1221142357gpos100
11p11.223572655gneg
11p11.1226552872gpos75
11p11.1128723035acen
11q1130353197acen
11q12.131973414gpos75
11q12.234143550gneg
11q12.335503685gpos25
11q13.136854037gneg
11q13.240374186gpos25
11q13.341864512gneg
11q13.445124688gpos50
11q13.546884877gneg
11q14.148775148gpos100
11q14.251485257gneg
11q14.352575474gpos100
11q2154745690gneg
11q22.156905934gpos100
11q22.259346070gneg
11q22.360706300gpos100
11q23.163006503gneg
11q23.265036693gpos50
11q23.366937167gneg
11q24.171677316gpos50
11q24.273167533gneg
11q24.375337695gpos50
11q2576957980gneg