Clamoxyquine
Clamoxyquine or clamoxyquin, as the pamoate or hydrochloride salt, is an antiamebic and antidiarrheal drug.
It has been used as a veterinary medicine to treat salmonids for infection with the myxozoan parasite Myxobolus cerebralis.Synthesis
Antimalarial activity also predominates in a quinoline that bears a diaminoalkyl side chain at a rather different position from the other agents noted.
Thus, Mannich condensation of the hydroxyquinoline with formaldehyde and N,N-diethylpropylenediamine affords clamoxyquin.
