The San Francisco 49ers selected Jones in the sixth round of the 2011NFL Draft. Jones was the 13th safety drafted in 2011. On July 29, 2011, the San Francisco 49ers signed Jones to a four-year, $2.13 million contract that includes a signing bonus of $100,000. Throughout training camp, Jones competed for a roster spot as a backup safety and special teams player against Madieu Williams, Curtis Taylor, Chris Maragos, and Anthony West. Head coachJim Harbaugh named Jones the third free safety on the depth chart to begin the regular season, behind Dashon Goldson and Madieu Williams. He made his professional regular season debut in the San Francisco 49ers' season-opening 33–17 victory against the Seattle Seahawks. Jones was inactive as a healthy scratch for three games. On December 4, 2011, Jones recorded a season-high two solo tackles in the 49ers' 26–0 win against the St. Louis Rams in Week 13. He finished his rookie season in 2011 with six solo tackles in 13 games and zero starts. The San Francisco 49ers finished first in the NFC West with a 13–3 record and earned a first round bye. On January 14, 2012, Jones appeared in his first career playoff game and recorded two solo tackles during their 36–32 win against the New Orleans Saints in the NFC Wildcard Game. The following week, he made one solo tackle as the 49ers lost 20–17 to the New York Giants in the NFC Championship Game. During training camp in 2012, Jones competed for a role as a backup safety against Trenton Robinson, Michael Thomas, Darcel McBath, Mark LeGree, and Ben Hannula.
Carolina Panthers
On August 31, 2012, the. San Francisco 49ers traded Jones to the Carolina Panthers for a seventh round pick in the 2014 NFL Draft. The 49ers used the selection to draft defensive tackleKaleb Ramsey. Head coach Ron Rivera named Jones the third free safety on the depth chart to begin the regular season, behind Haruki Nakamura and Sherrod Martin. Jones was inactive during the Panthers' Week 3 loss to the New York Giants due to an injury. In Week 8, Jones collected a season-high two solo tackles during a 23-22 loss at the Chicago Bears. Jones finished the season with 14 combined tackles in 15 games and zero starts. His first two years with the team his role was exclusively special teams, but started playing nickel corner and backup free safety in 2014. On June 18, 2014, Jones signed a two-year contract extension with the Panthers. In 2015, Jones recorded his first career interception in the Week 7 win against the Philadelphia Eagles quarterback Sam Bradford. On February 7, 2016, Jones was part of the Panthers team that played in Super Bowl 50. In the game, the Panthers fell to the Denver Broncos by a score of 24–10. On March 7, 2017, Jones signed a two-year contract extension with the Panthers. On March 11, 2019, Jones signed a two-year contract extension with the Panthers. The Panthers released Jones on March 16, 2020.
