Combined immunodeficiencies


Combined immunodeficiencies are immunodeficiency disorders that involve multiple components of the immune system, including both humoral immunity and cell-mediated immunity.
This category includes conditions such as bare lymphocyte syndrome, as well as severe combined immunodeficiency. Combined immunodeficiencies are commonly distinguished from SCID by low but not absent T-cell function.
ICD-9 divides immune deficiencies into three categories: humoral, cell-mediated, and combined. However, ICD-10 does not include a category for cell-mediated immune dysfunction, thus grouping T-cell mediated conditions with combined conditions.