Santee was a three-year starter at Flint Southwestern Academy. As a senior in 2001, he averaged 20 points and 7 assists per game, leading him to earn first team All-State honors. He also finished as the runner-up for Michigan's "Mr. Basketball" and was rated the number one point guard in the 2001 class in the state of Michigan by Prep Spotlight Magazine.
College career
After high school, Santee was recruited by coach Billy Tubbs to attend Texas Christian University in Fort Worth, Texas. After Santee's freshman year at TCU, Tubbs was replaced by Neil Dougherty, who came to TCU fresh from a trip to the Final Four as an assistant at Kansas. Santee was named Team MVP and All-Conference USA as both a junior and senior. In his junior season Corey started all 29 games at point guard and played a team-high 33.1 minutes per contest while ranking first on the team in scoring at 14.5 per contest and in assists at 4.4 per game. As a senior in 2005, he led his team with 14 ppg, 3 rpg, 4 assists. He scored a season high 26 points against Texas A&M-Corpus Christi. He towed the Horned Frogs to the quarterfinal round of the NIT. Corey Santee started 61 straight games for TCU and ended his college career as the all-time assists leader and also had 1,832 points, good for second on the school's all-time scoring list.
Professional career
Santee was on many NBA teams’ draft board but he went undrafted in the 2005 NBA draft. His first overseas experience was in Latvia with BK Ventspils, but it lasted only few weeks. Right afterwards he played professional basketball in Germany for the Sellbytel Baskets Nürnberg for a year before returning to play for the Fort Worth Flyers, playing both guard spots. He put up in 12.2 points, 1.5 assists and 1.0 steal a game in the 2006-2007 NBDL season and also ranked in the top five for three pointer made. Santee then played for Intercollege Etha in the Top Division in Cyprus, where he was one of the top three point shooters in Cyprus. He also led the Cyprus league in minutes played.. He played in Ukraine for Sumykhimprom Sumy.