Elisabeth's parents were Elector PalatineFrederick III and his wife Marie of Brandenburg-Kulmbach. She was the third child of the couple and the second who reached adulthood. On 12 June 1558 in Weimar, Elisabeth married Duke John Frederick II of Saxony, the eldest son of the Elector John Frederick "the Magnanimous" of Saxony. He selected Grimmenstein Castle in Gotha as their residence. During the Gotha War, Elector Augustus of Saxony besieged Gotha and Grimmenstein Castle and conquered them on 13 April 1567. John Frederick was taken prisoner and would spend the rest of his life in imperial captivity. He was brought to Dresden and in June 1567 to Wiener Neustadt. Duchess Elisabeth and her children fled to Eisenach and then to her sister Dorothea Susanne of Simmern, who was married to her husband's brother, Duke John William of Saxe-Weimar. At the end of 1568, she moved back to Eisenahch, initially to the Zollhof court, then to the Wartburg and finally into the castle at Eisenberg In the following years, Elisabeth wrote a number of petitions to, among others, Emperor Maximilian II, Empress Maria and Electress Anne of Saxony, trying to obtain the release of her husband. With the help of her father and brothers, she appeared before the Diet of Speyer. She was allowed to prostrate in front of Emperor Maximilian II at her father's Heidelberg Castle. The Emperor then reinstated her sons as Imperial Princes. Duke John William I acted as their guardian until the Division of Erfurt was made on 6 November 1572. After that Division, their guardians were Elector John George of Brandenburg and Elector Palatine Frederick III and Elector Augustus of Saxony, who provided them with an education under his supervision and in his spirit. In the summer of 1572, Elisabeth moved in with her husband in captivity in the castle of Wiener Neustadt. From there, she has returned twice more to Coburg. On 5 August 1572, her son Frederick Henry died in Eisenberg. Her two youngest sons John Casimir and John Ernest moved into the Ehrenburg Palace at Coburg on 5 December 1572, where they were raised by under the governorship of Count Barby, who was a confidant of Augustus. In June and July 1578, Elisabeth traveled via Prague, where they unsuccessfully tried to meet Dowager Empress Maria, to Coburg where she met with her younger sister Dorothea Susanna. In 1583, Elisabeth traveled in the period from March to August, via Prague and Coburg to Weimar to attend on 5 May at the wedding of Frederick William I with Sophie of Württemberg May 5, and to meet Elector Augustus. However, the Elector cancelled the appointment. On her return journey, she visited her brother Elector Palatine Louis VI in Heidelberg, where she was accompanied by her sons. Elisabeth died on 8 February 1594 in the armory of Wiener Neustadt. Her body was repatriated to Coburg at the end of the year and buried in the Morizkirche on 30 December 1594. In 1598, Duke John Casimir had a twelve-meter-high alabaster epitaph by the sculptor Nikolaus Bergner erected on the tomb of Elisabeth and John Frederick, who had died in 1595.
Marriage and issue
On 12 June 1558 in Weimar, Elisabeth married Duke John Frederick II of Saxony, the eldest son of the Elector John Frederick "the Magnanimous" of Saxony. They had four sons:
